Journal article
Emerging therapies for human hearing loss
E Ajay, N Gunewardene, R Richardson
Expert Opinion on Biological Therapy | Published : 2022
Abstract
Introduction: More than 5% of the world’s population have a disabling hearing loss which can be managed by hearing aids or implanted electrical devices. However, outcomes are highly variable, and the sound perceived by recipients is far from perfect. Sparked by the discovery of progenitor cells in the cochlea and rapid progress in drug delivery to the cochlea, biological and pharmaceutical therapies are currently in development to improve the function of the cochlear implant or eliminate the need for it altogether. Areas covered: This review highlights progress in emerging regenerative strategies to restore hearing and adjunct therapies to augment the cochlear implant. Novel approaches inclu..
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Grants
Awarded by National Health and Medical Research Council
Funding Acknowledgements
This paper was funded by the National Health and Medical Research Council (GNT2002523; Development Grant 2000202) and the University of Melbourne, Department of Engineering. The Bionics Institute acknowledges the support it receives from the Victorian Government through its Operational Infrastructure Support Program.