ROLLIS roll-out: Pitfalls, errors, lessons learned and recommendations from Australian and New Zealand experience during the randomised controlled trial, implementing a novel localisation method for impalpable malignant breast lesions, radio-guided occult lesion localisation with iodine-125 (125I) seed (ROLLIS)

AG Bourke; D Taylor; C Saunders

Journal article

ROLLIS roll-out: Pitfalls, errors, lessons learned and recommendations from Australian and New Zealand experience during the randomised controlled trial, implementing a novel localisation method for impalpable malignant breast lesions, radio-guided occult lesion localisation with iodine-125 (125I) seed (ROLLIS)

AG Bourke, D Taylor, C Saunders

Journal of Medical Imaging and Radiation Oncology | Published : 2022

DOI: 10.1111/1754-9485.13418

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Abstract

Introduction: Breast cancer surgery aims to excise lesions with clear margins and provide optimal cosmesis with a low re-excision rates. These aims are aided by accurate lesion localisation and a surgical choice of incision site with minimal removal of healthy tissue. Problems associated with hookwires have led to adoption of non-wire methods including radioguided occult lesion localisation using iodine-125 (ROLLIS). This paper outlines the problems encountered and lessons learnt during the largest RCT involving 659 participants, conducted at eight sites (seven Australian, one New Zealand centres) between September 2013 and April 2018.*. Methods: Data, along with substantive comments, regard..

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University of Melbourne Researchers

Christobel Saunders Author

Grants

Funding Acknowledgements

This study has been a team effort. We thank breast surgeons and Team Leads-Chilton Chong, Rhea Liang, Rebecca Hughes, Elizabeth Elder for their leadership and commitment to the ROLLIS programme. The support of the several funding bodies is gratefully acknowledged: Western Australia: The State Health Research Advisory Committee, The Royal Perth Hospital Medical Research Foundation, The Cancer Council of Western Australia, The St John of God Foundation, The Ladybird Foundation, Gold Coast Hospital and Health Service: Clinical Excellence Unit, Queensland Health. New Zealand: Southern Trust, Grassroots Trust, Lion Foundation, Waikato Breast Cancer Research Trust, Jumble Around. Open access publishing facilitated by The University of Western Australia, as part of the Wiley -The University of Western Australia agreement via the Council of Australian University Librarians.