Journal article
Imaging Breast Microcalcifications Using Dark-Field Signal in Propagation-Based Phase-Contrast Tomography
A Aminzadeh, BD Arhatari, A Maksimenko, CJ Hall, D Hausermann, AG Peele, J Fox, B Kumar, Z Prodanovic, M Dimmock, D Lockie, KM Pavlov, YI Nesterets, D Thompson, SC Mayo, DM Paganin, ST Taba, S Lewis, PC Brennan, HM Quiney Show all
IEEE Transactions on Medical Imaging | IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC | Published : 2022
Abstract
Breast microcalcifications are an important primary radiological indicator of breast cancer. However, microcalcification classification and diagnosis may be still challenging for radiologists due to limitations of the standard 2D mammography technique, including spatial and contrast resolution. In this study, we propose an approach to improve the detection of microcalcifications in propagation-based phase-contrast X-ray computed tomography of breast tissues. Five fresh mastectomies containing microcalcifications were scanned at different X-ray energies and radiation doses using synchrotron radiation. Both bright-field (i.e. conventional phase-retrieved images) and dark-field images were extr..
View full abstractGrants
Awarded by Australian National Breast Cancer Foundation
Awarded by National Health and Medical Research Council (NHMRC), Australia
Funding Acknowledgements
This work was supported in part by the Australian National Breast Cancer Foundation under Grant IN-16-001; in part by the National Health and Medical Research Council (NHMRC), Australia, under Grant APP1138283; and in part by Australia's Nuclear Sciences and Technology Organisation (ANSTO) Project Funding.