Journal article

Neurological factors and Cesarean section in Australian women with epilepsy

FJE Vajda, TJ O'Brien, JE Graham, AA Hitchcock, P Perucca, R Kuhn, CM Lander, MJ Eadie

Epilepsy and Behavior | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2022

Abstract

Objectives: To analyze the records of the pregnancies of 2283 Australian women with epilepsy in the Australian Register of Antiepileptic Drugs in Pregnancy database to identify neurological factors relevant to the Cesarean sections carried out in these pregnancies. Results: The Cesarean section rate in Australian women overall increased by an average of 0.59% annually over 20 years, from 26.0% to its calculated 2020 value of 37.3%. For the operations in women with epilepsy, the corresponding figures were 0.71% annually, and 34.4% and 48.7%. The average annual rate of increase for pre-labor operations was 0.89% to a 2020 value of 39.1%, the annual rate for operations during labor showing no s..

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University of Melbourne Researchers

Grants

Awarded by Sanofi


Funding Acknowledgements

We are grateful to professional and lay colleagues and bodies for referring patients to the APR, and to the Scientific Advisory Board and the Ethical Research Committees of St. Vincent?s Hospi-tal, Monash Medical Centre, the Royal Melbourne Hospital and other institutions for continuing ethics oversight of the APR. Over its years, The Epilepsy Society of Australia, The Royal Melbourne Hospital Neuroscience Foundation, Epilepsy Australia, the NHMRC and the pharmaceutical companies Sanofi-Aventis, UCB Pharma, Janssen-Cilag, Novartis, Sci-Gen, Eisai and Genzyme have provided financial support toward maintaining the APR at various stages of its existence.