Childhood bronchitis' and respiratory outcomes in middle-age: a prospective cohort study from age 7 to 53 years

JL Perret; D Wurzel; E Haydn Walters; AJ Lowe; CJ Lodge; DS Bui; B Erbas; G Bowatte; MA Russell; BR Thompson; L Gurrin; PS Thomas; G Hamilton; JL Hopper; MJ Abramson; AB Chang; SC Dharmage

Journal article

Childhood bronchitis' and respiratory outcomes in middle-age: a prospective cohort study from age 7 to 53 years

JL Perret, D Wurzel, E Haydn Walters, AJ Lowe, CJ Lodge, DS Bui, B Erbas, G Bowatte, MA Russell, BR Thompson, L Gurrin, PS Thomas, G Hamilton, JL Hopper, MJ Abramson, AB Chang, SC Dharmage

BMJ Open Respiratory Research | Published : 2022

DOI: 10.1136/bmjresp-2022-001212

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Abstract

Background Chronic bronchitis in childhood is associated with a diagnosis of asthma and/or bronchiectasis a few years later, however, consequences into middle-age are unknown. Objective To investigate the relationship between childhood bronchitis and respiratory-related health outcomes in middle-age. Design Cohort study from age 7 to 53 years. Setting General population of European descent from Tasmania, Australia. Participants 3202 participants of the age 53-year follow-up (mean age 53, range 51-55) of the Tasmanian Longitudinal Health Study cohort who were born in 1961 and first investigated at age 7 were included in our analysis. Statistical methods Multivariable linear and logistic regre..

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University of Melbourne Researchers

Jennifer Perret Author

Danielle Wurzel Author

Adrian Lowe Author

Caroline Lodge Author

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Grants

Awarded by Boehringer Ingelheim

Funding Acknowledgements

The TAHS was supported by the National Health and Medical Research Council (NHMRC) of Australia, research grants 299901 and 1021275; the University of Melbourne; Clifford Craig Foundation; the Victorian, Queensland and Tasmanian Asthma Foundations; Royal Hobart Hospital; Helen MacPherson Smith Trust; and GlaxoSmithKline. JP, AL, ABC and SCD are funded through the NHMRC of Australia. DW is funded by a fellowship from the NHMRC CRE in bronchiectasis (AusBREATHE). ABC is also supported by the Queensland Children's Foundation.