PEARL: A randomised phase 3 trial of palliative care early in advanced lung cancers (ALTG/TOGA 13/008).

Linda R Mileshkin; Jaclyn Yoong; Renee Eggins; Jennifer Philip; Chris Brown; Gavin Michael Wright; Annette Tognela; Prunella Blinman; Peter Poon; Anna K Nowak; Andrew Oar; Nick Pavlakis; Mariya Walker; Jennifer Chong; Hannora Jurkovic; Ratnesh Kumar Srivastav; Ehtesham A Abdi; Antony Mersiades; Rajesh Thomas; Martin R Stockler

Conference Proceedings

PEARL: A randomised phase 3 trial of palliative care early in advanced lung cancers (ALTG/TOGA 13/008).

Linda R Mileshkin, Jaclyn Yoong, Renee Eggins, Jennifer Philip, Chris Brown, Gavin Michael Wright, Annette Tognela, Prunella Blinman, Peter Poon, Anna K Nowak, Andrew Oar, Nick Pavlakis, Mariya Walker, Jennifer Chong, Hannora Jurkovic, Ratnesh Kumar Srivastav, Ehtesham A Abdi, Antony Mersiades, Rajesh Thomas, Martin R Stockler

JOURNAL OF CLINICAL ONCOLOGY | LIPPINCOTT WILLIAMS & WILKINS | Published : 2022

DOI: 10.1200/jco.2022.40.16_suppl.12020

Abstract

12020 Background: Early referral to palliative care was associated with improved health-related quality of life (HRQL) and overall survival (OS) in a US phase 3 trial in lung cancer patients (pts). International studies in mixed cancer types have reported conflicting results. PEARL aimed to determine whether early referral to palliative care would improve HRQL, OS, and resource use in Australian pts with recently diagnosed, advanced thoracic cancers. Methods: Eligible participants (pts) in this unblinded, multi-centre, randomised, phase 3 trial had advanced thoracic cancers diagnosed within 60 days, and the ability to complete patient-rated outcome measures (PROMS). Pts were randomly alloca..

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