Journal article
Breastmilk influences development and composition of the oral microbiome
CA Butler, GG Adams, J Blum, SJ Byrne, L Carpenter, MG Gussy, H Calache, DV Catmull, EC Reynolds, SG Dashper
Journal of Oral Microbiology | TAYLOR & FRANCIS LTD | Published : 2022
Abstract
Background: Human microbiomes assemble in an ordered, reproducible manner yet there is limited information about early colonisation and development of bacterial communities that constitute the oral microbiome. Aim: The aim of this study was to determine the effect of exposure to breastmilk on assembly of the infant oral microbiome during the first 20 months of life. Methods: The oral microbiomes of 39 infants, 13 who were never breastfed and 26 who were breastfed for more than 10 months, from the longitudinal VicGeneration birth cohort study, were determined at four ages. In total, 519 bacterial taxa were identified and quantified in saliva by sequencing the V4 region of the bacterial 16S rR..
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Awarded by Financial Markets Foundation for Children
Funding Acknowledgements
This research was supported by: The National Health and Medical Research Council (Primary Health Care Project Grant 425829); Dental Health Services Victoria; Financial Markets Foundation for Children; Jack Brockhoff Foundation; La Trobe University, the Victorian Government Department for Education and Training and the Australian Government Department of Industry, Innovation and Science Grant ID 20080108 through the Oral Health Cooperative Research Centr; Department of Industry, Innovation and Science, Australian Government