Journal article
Computerized cognitive training in Parkinson's disease: A systematic review and meta-analysis
HM Gavelin, ME Domellöf, I Leung, AS Neely, NH Launder, L Nategh, C Finke, A Lampit
Ageing Research Reviews | Published : 2022
Abstract
Cognitive impairment is a central non-motor symptom of Parkinson's disease (PD), and there are no established treatments. Computerized cognitive training (CCT) is a safe and efficacious strategy but its efficacy in PD is unclear. We aimed to investigate the efficacy of CCT on cognitive, psychosocial and daily function, and assess potential effect moderators in people with PD without dementia. Randomized controlled trials of CCT were included in multivariate meta-analyses and meta-regressions. Seventeen studies (16 trials) encompassing 679 participants were included. The pooled effect of CCT relative to control was small and statistically significant for overall cognitive function (g=0.16; 95..
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Awarded by University of Melbourne
Funding Acknowledgements
Study funding This work was supported by a CR Roper Fellowship from the University of Melbourne provided to AL (2020-1) , and by the Swedish Research Council (2017-02371) as well as the Swedish Research Council for Health, Working-Life and Welfare (2014-01654) awarded to ASN.