Diet and risk of Barrett's oesophagus: Melbourne collaborative cohort study

SE Wang; A Hodge; SG Dashti; SC Dixon-Suen; N Castaño-Rodríguez; R Thomas; G Giles; A Boussioutas; B Kendall; DR English

Journal article

Diet and risk of Barrett's oesophagus: Melbourne collaborative cohort study

SE Wang, A Hodge, SG Dashti, SC Dixon-Suen, N Castaño-Rodríguez, R Thomas, G Giles, A Boussioutas, B Kendall, DR English

British Journal of Nutrition | Published : 2023

DOI: 10.1017/S0007114522002112

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Abstract

Barrett's oesophagus (BE) is the precursor of oesophageal adenocarcinoma, which has become the most common type of oesophageal cancer in many Western populations. Existing evidence on diet and risk of BE predominantly comes from case-control studies, which are subject to recall bias in measurement of diet. We aimed to investigate the potential effect of diet, including macronutrients, carotenoids, food groups, specific food items, beverages and dietary scores, on risk of BE in over 20 000 participants of the Melbourne Collaborative Cohort Study. Diet at baseline (1990-1994) was measured using a food frequency questionnaire. The outcome was BE diagnosed between baseline and follow-up (2007-20..

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University of Melbourne Researchers

Allison Hodge Author

Ghazaleh Dashti Author

Robert Thomas Author

Graham Giles Author

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Grants

Awarded by Australian National Health and Medical Research Council

Awarded by NHMRC

Awarded by Cancer Institute NSW Early Career Fellowship (NCR)

Funding Acknowledgements

The Melbourne Collaborative Cohort Study cohort recruitment was funded by VicHealth and Cancer Council Victoria. The Melbourne Collaborative Cohort Study was further augmented by Australian National Health and Medical Research Council grants (grant number 209057, 396414 and 1074383) and by infrastructure provided by Cancer Council Victoria. The study of gastroesophageal reflux and Barrett's oesophagus was funded by a NHMRC project grant (grant number 504708). This work was further supported by an Australian Government Research Training Program Scholarship (SEW), a Cancer Institute NSW Early Career Fellowship (NCR, grant number 2019/ECF1082) and a UNSW Scientia Fellowship (NCR).