Insulin antibodies are prevalent in adults with type 1 diabetes referred for islet cell transplantation and are modified by islet transplantation and immunosuppression: an Australian experience

CJ Hensman; JL Gooley; AS Januszewski; MH Lee; RJ MacIsaac; RC Boston; P O'Connell; N Rogers; J Holmes-Walker; W Hawthorne; P Anderson; A Webster; S Alexander; E Jimenez-Vera; M Hu; S Yi; K Ghimire; A Thomas; B Delalat; L Joo; T Kay; D Goodman; GM Ward; R MacIsaac; C Kos; F Ierino; K Howe; L Mariani; M Waibel; T Brodniki; T Loudovaris; H Thomas; AJ Jenkins; T Coates; C Drogemuller; C Etherton; D Torpy; S Kireta; T Radford; A Rickard; S Grey

Journal article

Insulin antibodies are prevalent in adults with type 1 diabetes referred for islet cell transplantation and are modified by islet transplantation and immunosuppression: an Australian experience

CJ Hensman, JL Gooley, AS Januszewski, MH Lee, RJ MacIsaac, RC Boston, P O'Connell, N Rogers, J Holmes-Walker, W Hawthorne, P Anderson, A Webster, S Alexander, E Jimenez-Vera, M Hu, S Yi, K Ghimire, A Thomas, B Delalat, L Joo Show all

Internal Medicine Journal | Published : 2022

DOI: 10.1111/imj.15867

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Abstract

We have analysed insulin antibodies in 149 adults with type 1 diabetes and 2859 people without diabetes. We have determined that insulin antibody levels are higher in adults with, versus without, diabetes and that the levels are falling, and more patients are becoming antibody-negative post islet cell transplantation.