Journal article
Lung volume changes during apnoeas in preterm infants
VD Gaertner, AD Waldmann, PG Davis, D Bassler, L Springer, DG Tingay, CM Rüegger
Archives of Disease in Childhood Fetal and Neonatal Edition | BMJ PUBLISHING GROUP | Published : 2023
Abstract
Objective Mechanisms of non-invasive high-frequency oscillatory ventilation (nHFOV) in preterm infants are unclear. We aimed to compare lung volume changes during apnoeas in preterm infants on nHFOV and nasal continuous positive airway pressure (nCPAP). Methods Analysis of electrical impedance tomography (EIT) data from a randomised crossover trial comparing nHFOV with nCPAP in preterm infants at 26-34 weeks postmenstrual age. EIT data were screened by two reviewers to identify apnoeas ≥10 s. End-expiratory lung impedance (EELI) and tidal volumes (V T) were calculated before and after apnoeas. Oxygen saturation (SpO2) and heart rate (HR) were extracted for 60 s after apnoeas. Results In 30 p..
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Grants
Awarded by State Government of Victoria
Funding Acknowledgements
VDG received an Endeavour Research Fellowship by the Australian Government (ERF_RDDH_5276_2016), PGD is supported by the Victorian Government Operational Infrastructure Support Programme (Melbourne, Australia) and the National Health and Medical Research Council (Practitioner Fellowship GNT 1059111), LS received a grant from the German Research Society (LO 2162/1-1), DGT received Career Development Fellowships by the NHMRC (GNT 11123859 and 1057514), and CMR was supported by the Swiss National Science Foundation (Early Postdoctoral Mobility fellowship P2ZHP3_161749) and the Swiss Society of Neonatology (Milupa Fellowship Award).