Intelligence trajectories in individuals at ultra-high risk for psychosis: An 8-year longitudinal analysis

N Cheng; A Lin; S Bowden; C Gao; AR Yung; B Nelson; A Thompson; HP Yuen; WJ Brewer; D Cagliarini; A Bruxner; M Simmons; C Broussard; C Pantelis; PD McGorry; K Allott; SJ Wood

Journal article

Intelligence trajectories in individuals at ultra-high risk for psychosis: An 8-year longitudinal analysis

N Cheng, A Lin, S Bowden, C Gao, AR Yung, B Nelson, A Thompson, HP Yuen, WJ Brewer, D Cagliarini, A Bruxner, M Simmons, C Broussard, C Pantelis, PD McGorry, K Allott, SJ Wood

Schizophrenia Research | Published : 2022

DOI: 10.1016/j.schres.2022.08.006

Abstract

Cognitive impairment is a well-documented predictor of transition to a full-threshold psychotic disorder amongst individuals at ultra-high risk (UHR) for psychosis. However, less is known about whether change in cognitive functioning differs between those who do and do not transition. Studies to date have not examined trajectories in intelligence constructs (e.g., acquired knowledge and fluid intelligence), which have demonstrated marked impairments in individuals with schizophrenia. This study aimed to examine intelligence trajectories using longitudinal data spanning an average of eight years, where some participants completed assessments over three time-points. Participants (N = 139) at U..

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University of Melbourne Researchers

Stephen Bowden Author

Caroline Gao Author

Barnaby Nelson Author

Andrew Thompson Author

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Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

The PACE studies were supported by National Health and Medical Research Council (NHMRC) program grants (#350241 and #566529) and the Colonial Foundation. SJW was supported by National Health and Medical Research Council (NHMRC) Career Development Awards. KA was supported by a Career Development Fellowship from the National Health and Medical Research Council (NHMRC: APP1141207) and a Dame Kate Campbell Fellowship from the University of Melbourne. The funders played no role in the collection, analysis, or publication of data.