Cost-effectiveness of universal iron supplementation and iron-containing micronutrient powders for anemia among young children in rural Bangladesh: analysis of a randomized, placebo-controlled trial

E Akpan; SJ Hossain; A Devine; S Braat; MI Hasan; SM Mulk Uddin Tipu; MSA Bhuiyan; JD Hamadani; BA Biggs; SR Pasricha; N Carvalho

Journal article

Cost-effectiveness of universal iron supplementation and iron-containing micronutrient powders for anemia among young children in rural Bangladesh: analysis of a randomized, placebo-controlled trial

E Akpan, SJ Hossain, A Devine, S Braat, MI Hasan, SM Mulk Uddin Tipu, MSA Bhuiyan, JD Hamadani, BA Biggs, SR Pasricha, N Carvalho

American Journal of Clinical Nutrition | ELSEVIER SCIENCE INC | Published : 2022

DOI: 10.1093/ajcn/nqac225

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Abstract

Background: Universal provision of iron supplements or iron-containing multiple micronutrient powders (MNPs) is widely used to prevent anemia in young children in low- and middle-income countries. The BRISC (Benefits and Risks of Iron Interventions in Children) trial compared iron supplements and MNPs with placebo in children <2 y old in rural Bangladesh. Objectives: We aimed to assess the cost-effectiveness of iron supplements or iron-containing MNPs among young children in rural Bangladesh. Methods: We did a cost-effectiveness analysis of MNPs and iron supplements using the BRISC trial outcomes and resource use data, and programmatic data from the literature. Health care costs were assesse..

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University of Melbourne Researchers

Angela Devine Author

Sabine Braat Author

Beverley-Ann Biggs Author

Sant-Rayn Pasricha Author

Related Projects (1)

DEFINING THE IMPACT OF UNIVERSAL IRON INTERVENTIONS IN YOUNG CHILDREN: A RANDOMIZED CONTROLLED TRIAL IN RURAL BANGLADESH

Although nearly half of the world's young children are anaemic, evidence regarding the best approaches to correct this problem are limited. ..

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Funding Acknowledgements

The authors' responsibilities were as follows-EA, S-RP, NC, AD, and SJH: designed the research; EA, SJH, SB, MIH, SMMUT, MSAB, JDH, and S-RP: conducted the research; SJH and SB: provided essential materials; EA: analyzed the data; EA, AD, NC, S-RP, and SJH: wrote the paper; SJH, SB, MIH, SMMUT, MSAB, JDH, BA-B, and S-RP: designed the BRISC trial; S-RP, NC, and AD: supervised the research; and all authors: read and approved the final manuscript. B-AB reports grants from the National Health andMedical Research Council (NHMRC) during the conduct of the study. SRP reports grants from the NHMRC and Bill and Melinda Gates Foundation during the conduct of the study, as well as personal fees from Vifor Pharma and Keros Pharma. NC reports grants from the NHMRC during the conduct of the study. All other authors report no conflicts of interest.