Hyaluronic acid rectal spacer in EBRT: Usability, safety and symmetry related to user experience

J Williams; KM Millan; D Bolton; A Tan; CW Cham; T Pham; D Pan; M Liu; Y Chan; P Manohar; J Thomas; G Koufogiannis; H Ho; M Guerrieri; M Ng; T Boike; C Macleod; DL Joon; F Foroudi; M Chao

Journal article

Hyaluronic acid rectal spacer in EBRT: Usability, safety and symmetry related to user experience

J Williams, KM Millan, D Bolton, A Tan, CW Cham, T Pham, D Pan, M Liu, Y Chan, P Manohar, J Thomas, G Koufogiannis, H Ho, M Guerrieri, M Ng, T Boike, C Macleod, DL Joon, F Foroudi, M Chao

Journal of Medical Imaging and Radiation Sciences | ELSEVIER SCIENCE INC | Published : 2022

DOI: 10.1016/j.jmir.2022.09.008

Abstract

Objectives: To report on the usability, safety, symmetry, and effectiveness of hyaluronic acid (HA) injected between the prostate and the rectum for patients undergoing treatment for prostate cancer with external beam radiotherapy (EBRT), and present a novel definition of rectal spacer symmetry that is reproducible and independent of patient anatomy. Patients and Methods: 102 consecutive patients with clinical stage of T1c-3b prostate cancer underwent general anaesthesia for fiducial marker insertion and injection of HA into the perirectal space before EBRT. HA safety, symmetry, separation, and usability based on user experience were assessed. Results: HA insertion was completed with a 100% ..

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