Journal article

Open problems in mathematical biology

ST Vittadello, MPH Stumpf

Mathematical Biosciences | ELSEVIER SCIENCE INC | Published : 2022

Abstract

Biology is data-rich, and it is equally rich in concepts and hypotheses. Part of trying to understand biological processes and systems is therefore to confront our ideas and hypotheses with data using statistical methods to determine the extent to which our hypotheses agree with reality. But doing so in a systematic way is becoming increasingly challenging as our hypotheses become more detailed, and our data becomes more complex. Mathematical methods are therefore gaining in importance across the life- and biomedical sciences. Mathematical models allow us to test our understanding, make testable predictions about future behaviour, and gain insights into how we can control the behaviour of bi..

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University of Melbourne Researchers

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Funding Acknowledgements

The authors thank the members of the Theoretical Systems Biology group, past and present, for stimulating discussions that have shaped our view. Much of the conceptual work has been the result of our ongoing collaborations, especially in MACSYS. Both authors acknowl-edge the financial support from the Volkswagen Foundation, Germany through a Life program grant.