Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway

Grants

Funding Acknowledgements

We dedicate this manuscript in memory of Associate Professor Katherine M. Hannan. Our sincerest thanks to the Captain Courageous Foundation (cap-taincourageous.com .au) in particular, Jessica and Jeff Bond, and Bill Steele for their ongoing support and funding for this project. We would like to acknowledge the founding and current members of the Australian Diamond Blackfan Anaemia (ADBA) program, consisting of Sheren J. Al-Obaidi, Luen Bik To, Sarah C.E. Bray, Richard J. DeAndrea, Jianmin Ding, Amee J. George, Thomas J. Gonda, Ross D. Hannan, Melissa Ilsley, S. Peter Klinken, Lorena Ninez-Villacs, Richard B. Pearson, Ben Saxon, Hamish S. Scott, Adam Stephenson, Adam Stevenson, Parvathy Venugopal, Amilia Wee, Louise N. Win-teringham, and Mei Szin Wong. Our sincerest thanks go to Yanping Zhang (UNC Chapel Hill, USA) for providing the Mdm2 mouse strain used in this work. We would also like to thank Prof. George Thomas (IDIBELL, Spain) for his valuable discussions. We would like to thank Dr. Maurits Evers (bioinfor-matics and data visualization) , Prof. Eduardo Eyras and Dr. Adria Closa Mos-quera, the Imaging and Cytometry Facility (Dr. Harpreet Vohra and Mr. Michael Devoy) , the ANU Bioinformatics Consultancy (Dr. Zhi-Ping Feng and Mr. Ca-meron Jack) , and the staff at the Australian Phenomics Facility, the ACRF Bio-molecular Resource Facility, and the ANU Center for Therapeutic Discovery at the John Curtin School of Medical Research at the Australian National Univer-sity for their assistance. We would also like to thank the ACRF Victorian Center for Functional Genomics (Ms. Jennii Luu and Mr. Daniel Thomas) , the Molec-ular Genomics Core (Dr. Gisela Mir Arneau and Ms. Aga Borcz) , the Bioinfor-matics Core (Mr. Jason Ellul) , and the Advanced Center for Cancer Cell Isola-tion and Flow Cytometry (Ms. Viki Milovac and Ms. Sophie Curcio) located at the Peter MacCallum Cancer Center for their technical assistance, and all members of the Engel lab, especially Philipp Becker and Mona H?cherl. This work was supported by funding from the Captain Courageous Foundation and the National Health and Medical Research Council (NHMRC) of Australia (Project Grants #1100654, #1158732, #1102609, Program Grant #1053792, and Senior Research Fellowships to R.D.H. [#1116999] and R.B.P. [#1058586] ) . C.E. is supported by the Emmy-Noether-Programme, DFG grant no. EN 1204/1-1. U.K. was supported by the Swiss National Science Foundation (SNSF) (grant 31003A_166565 and the NCCR RNA and disease) . N.J.W. is supported by funding from the DBAF, DBA UK, and the BBSRC (BB/R00143X/1) . A.J.G. is supported by a Captain Courageous Foundation Fellow-ship. The Victorian Center for Functional Genomics (K.J.S.) is funded by the Australian Cancer Research Foundation (ACRF) and Phenomics Australia, through funding from the Australian Governments National Collaborative Research Infrastructure Strategy (NCRIS) program and the Peter MacCallumCancer Centre Foundation. The ANU Center for Therapeutic Discovery (A.J.G.) is funded by the ACRF, Australian National University, ACT Health, and Phe-nomics Australia (NCRIS) .