Journal article
The global distribution and environmental drivers of the soil antibiotic resistome
M Delgado-Baquerizo, HW Hu, FT Maestre, CA Guerra, N Eisenhauer, DJ Eldridge, YG Zhu, QL Chen, P Trivedi, S Du, TP Makhalanyane, JP Verma, B Gozalo, V Ochoa, S Asensio, L Wang, E Zaady, JG Illán, C Siebe, T Grebenc Show all
Microbiome | BMC | Published : 2022
Abstract
Background: Little is known about the global distribution and environmental drivers of key microbial functional traits such as antibiotic resistance genes (ARGs). Soils are one of Earth’s largest reservoirs of ARGs, which are integral for soil microbial competition, and have potential implications for plant and human health. Yet, their diversity and global patterns remain poorly described. Here, we analyzed 285 ARGs in soils from 1012 sites across all continents and created the first global atlas with the distributions of topsoil ARGs. Results: We show that ARGs peaked in high latitude cold and boreal forests. Climatic seasonality and mobile genetic elements, associated with the transmission..
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Awarded by Horizon 2020 Framework Programme
Funding Acknowledgements
This project received funding from the European Union's Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement 702057 (CLIMIFUN), a Large Research Grant from the British Ecological Society (agreement no. LRA17\1193; MUSGONET), and from the European Research Council (ERC grant agreement no. 647038, BIODESERT). M. D. B. was also supported by a Ramon y Cajal grant (RYC2018-025483-I). M.D-B. also acknowledges support from the Spanish Ministry of Science and Innovation for the I+D+i project PID2020-115813RA-I00 funded by MCIN/AEI/10.13039/501100011033. M.D-B. is also supported by a project of the Fondo Europeo de Desarrollo Regional (FEDER) and the Consejeria deTransformacioen Econoemica, Industria, Conocimiento y Universidades of the Junta de Andalucia (FEDER Andalucia 2014-2020 Objetivo tematico "01 - Refuerzo de la investigacioen, el desarrollo tecnoloegico y la innovacioen") associated with the research project P20_00879 (ANDABIOMA). FTM acknowledges support from Generalitat Valenciana (CIDEGENT/2018/041). J. Z. H and H. W. H. are financially supported by Australian Research Council (DP210100332). We also thank the project CTM2015-64728-C2-2-R from the Ministry of Science of Spain. C. A. G. and N. E. acknowledge funding by the German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig, funded by the German Research Foundation (FZT 118). TG was financially supported by Slovenian Research Agency (P4-0107, J4-3098 and J4-4547).