Journal article

Anesthesia and Developing Brains: Unanswered Questions and Proposed Paths Forward

C Ing, DO Warner, LS Sun, RP Flick, AJ Davidson, L Vutskits, ME McCann, J O’Leary, DC Bellinger, undefined Rauh, BA Orser, S Suresh, DB Andropoulos

Obstetric Anesthesia Digest | Ovid Technologies (Wolters Kluwer Health) | Published : 2022

Abstract

(Anesthesiology. 2022;136:500–512. doi: 10.1097/ALN.0000000000004116) Decades ago, some studies showed early exposure to anesthetics increased the risk of altered neurodevelopment while others showed no such association. The debate about any association between anesthesia and neurodevelopment continues today. As these questions affect millions of children who undergo anesthetic-requiring procedures, this report aimed to provide current preclinical and clinical evidence, unanswered questions, and research suggestions going forward.

University of Melbourne Researchers