Journal article
Abstract 11615: The Prevalence and Association of Exercise Test Abnormalities With Sudden Cardiac Death and Transplant-Free Survival in Childhood Hypertrophic Cardiomyopathy
Jennifer Conway, Sandar Min, Chet Villa, Robert G Weintraub, Stephanie J Nakano, Justin Godown, Armstrong Kathyrn, Marc E Richmond, Beth D Kaufman, Ashwin K Lal, Seshadri Balaji, Alyssa Power, Letizia Gardin, Paul F Kantor, John J Parent, Peter F Aziz, John L Jefferies, Tanya Papaz, Aamir Jeewa, Lee N Benson Show all
Circulation | Ovid Technologies (Wolters Kluwer Health) | Published : 2022
Abstract
Introduction: Hypertrophic cardiomyopathy (HCM) can be associated with an abnormal exercise response. In adults with HCM, an abnormal exercise stress test (EST) is predictive of heart failure outcomes. Our goal was to determine if an abnormal exercise response is associated with adverse outcomes in pediatric HCM patients. Methods: : In an international cohort study with 20 centers (PRIMaCY), children <18 years with primary HCM were included. Abnormal EST was defined as an abnormal heart rate or blood pressure response, arrhythmias and/or ischemic ECG changes on exercise. Sudden cardiac death (SCD) events were defined as a composite of..
View full abstract