Journal article

A Prospective, Multicentre Randomised Controlled Trial Comparing Catheter Ablation Versus Antiarrhythmic Drugs in Patients With Structural Heart Disease Related Ventricular Tachycardia: The CAAD-VT Trial Protocol

RG Bennett, T Campbell, K Garikapati, Y Kotake, S Turnbull, J Kanawati, MS Wong, P Qian, SP Thomas, CK Chow, P Kovoor, A Robert Denniss, W Chik, S Marschner, P Kistler, H Haqqani, M Rowe, A Voskoboinik, G Lee, N Jackson Show all

Heart Lung and Circulation | Published : 2023

Abstract

Importance: Randomised trials have shown that catheter ablation (CA) is superior to medical therapy for ventricular tachycardia (VT) largely in patients with ischaemic heart disease. Whether this translates to patients with all forms and stages of structural heart disease (SHD—e.g., non-ischaemic heart disease) is unclear. This trial will help clarify whether catheter ablation offers superior outcomes compared to medical therapy for VT in all patients with SHD. Objective: To determine in patients with SHD and spontaneous or inducible VT, if catheter ablation is more efficacious than medical therapy in control of VT during follow-up. Design: Randomised controlled trial including 162 patients,..

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University of Melbourne Researchers