School-age outcomes among IVF-conceived children: A population-wide cohort study

Abstract

Background AU In vitro: fertilisation (IVF) is a common mode of conception. Understanding : the long-term implications for these children is important. TheAU aim: of Theaimo this study was to determine the causal effect of IVF conception on primary school-age childhood developmental and educational outcomes, compared with outcomes following spontaneous conception. Methods and findings Causal inference methods were used to analyse observational data in a way that emulates a target randomised clinical trial. The study cohort comprised statewide linked maternal and childhood administrative data. Participants included singleton infants conceived spontaneously or via IVF, born in Victoria, Austra..