Journal article

Cognitive dysfunction and functional disability in alcohol-dependent adults with or without a comorbid affective disorder

RSC Lee, G Dore, L Juckes, T De Regt, SL Naismith, J Lagopoulos, A Tickell, IB Hickie, DF Hermens

Cognitive Neuropsychiatry | ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD | Published : 2015

Abstract

Introduction. Little is known about the relationship between cognitive dysfunction and functional disability in alcohol dependence with comorbid affective disorders. We investigated the neuropsychology of alcohol dependence in detoxified adults with and without affective comorbidity and examined the factors associated with prolonged functional disability. Methods. From a total of 42 participants (age range = 18-44 years), 12 out of 21 alcohol-dependent participants had a comorbid affective disorder, 12 had an affective disorder only, and 9 were healthy controls. Participants completed a semi-structured clinical interview, questionnaires and comprehensive neuropsychological assessment. Result..

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University of Melbourne Researchers

Grants

Awarded by NHMRC Centre of Research Excellence in Optimising Early Interventions for Young People with Emerging Mood Disorders


Awarded by NHMRC


Awarded by NHMRC Australia


Funding Acknowledgements

Funding for this study was partly provided by the NSW Department of Health. RSCL was supported by the NHMRC Centre of Research Excellence in Optimising Early Interventions for Young People with Emerging Mood Disorders (1061043). DFH was supported by a grant from the NSW Ministry of Health, Mental Health and Drug & Alcohol Office. SLN was supported by an NHMRC Career Development Award (402864). IBH was supported by an NHMRC Australia fellowship (464914). The views expressed in this paper are those of the authors and do not necessarily reflect those of the funding bodies. The funding bodies had no further role in study design; in the collection, analysis and interpretation of data; in the writing of the report; or in the decision to submit the paper for publication.