Occult Contrast Retention Post-thrombectomy On 24-hour Follow-up CT: Associations And Impact On Imaging Analysis

Jenny Pham; Calvin Gan; Jasmin Dabboucy; Damien Stella; Richard Dowling; Bernard Yan; Steven Bush; Cameron Williams; Peter J Mitchell; Patricia Desmond; Vincent Thijs; Hamed Asadi; Mark Brooks; Julian Maingard; Ash Jhamb; Davor Pavlin-Premrl; Bruce Campbell; Felix Ng

Journal article

Occult Contrast Retention Post-thrombectomy On 24-hour Follow-up CT: Associations And Impact On Imaging Analysis

Jenny Pham, Calvin Gan, Jasmin Dabboucy, Damien Stella, Richard Dowling, Bernard Yan, Steven Bush, Cameron Williams, Peter J Mitchell, Patricia Desmond, Vincent Thijs, Hamed Asadi, Mark Brooks, Julian Maingard, Ash Jhamb, Davor Pavlin-Premrl, Bruce Campbell, Felix Ng

STROKE | LIPPINCOTT WILLIAMS & WILKINS | Published : 2023

DOI: 10.1161/str.54.suppl_1.WMP49

Abstract

Introduction: CT performed 24h post-treatment is widely used to assess radiological outcomes in stroke studies. Even without visible hyperattenuation, occult angiographic contrast may persist in the brain and confound Hounsfield Unit-based imaging metrics such as Net Water Uptake (NWU), a measure of cerebral edema based on tissue hypoattenuation. We aimed to assess (1) the presence of retained contrast post-thrombectomy on 24h CT by comparing NWU measurements with and without adjustment for iodine using dual energy CT (DECT), (2) factors associated with amount of retention, and (3) its impact on the accuracy of NWU. Methods: In a pros..

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