Journal article
Screening for Coronary Artery Disease in Cancer Survivors JACC: CardioOncology State-of-the-Art Review
Ragani Velusamy, Mark Nolan, Andrew Murphy, Paaladinesh Thavendiranathan, Thomas H Marwick
JACC: CARDIOONCOLOGY | ELSEVIER | Published : 2023
Open access
Abstract
Coronary artery disease (CAD) is an important contributor to the cardiovascular burden in cancer survivors. This review identifies features that could help guide decisions about the benefit of screening to assess the risk or presence of subclinical CAD. Screening may be appropriate in selected survivors based on risk factors and inflammatory burden. In cancer survivors who have undergone genetic testing, polygenic risk scores and clonal hematopoiesis markers may become useful CAD risk prediction tools in the future. The type of cancer (especially breast, hematological, gastrointestinal, and genitourinary) and the nature of treatment (radiotherapy, platinum agents, fluorouracil, hormonal ther..
View full abstractGrants
Awarded by National Health and Medical Research Council, Canberra, Australia
Awarded by Canadian Institutes of Health Research New Investigator Award
Funding Acknowledgements
Dr Marwick was supported by an Investigator grant from the National Health and Medical Research Council, Canberra, Australia (No. 2008129) . Dr Thavendiranathan was supported by the Canadian Institutes of Health Research New Investigator Award (No. 147814) , the Ontario Early Research Award, and a Canada Research Chair in Cardio-Oncology. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.