Polygenic risk scores are associated with atrial electrophysiologic substrate abnormalities and outcomes after atrial fibrillation catheter ablation

A Al-Kaisey; GR Wong; P Young; D Chieng; J Hawson; R Anderson; H Sugumar; C Nalliah; M Prabhu; R Johnson; M Soka; I Tarr; A Bakshi; C Yu; P Lacaze; E Giannoulatou; A McLellan; G Lee; PM Kistler; D Fatkin; JM Kalman

Journal article

Polygenic risk scores are associated with atrial electrophysiologic substrate abnormalities and outcomes after atrial fibrillation catheter ablation

A Al-Kaisey, GR Wong, P Young, D Chieng, J Hawson, R Anderson, H Sugumar, C Nalliah, M Prabhu, R Johnson, M Soka, I Tarr, A Bakshi, C Yu, P Lacaze, E Giannoulatou, A McLellan, G Lee, PM Kistler, D Fatkin Show all

Heart Rhythm | Published : 2023

DOI: 10.1016/j.hrthm.2023.02.011

University of Melbourne Researchers

Geoff Wong Author

Alexander McLellan Author

Geoffrey Lee Author

Peter Kistler Author

Grants

Awarded by National Institutes of Health

Funding Acknowledgements

Funding Sources: The authors acknowledge funding support from the National Health and Medical Research Council (NHMRC) of Australia: Practitioner Fellowship (Dr Kalman) , Research Scholarships (Drs Al-Kaisey, Wong, Anderson, Chieng, and Sugumar) ; Heart Foundation: Future Leader Fellowship (Dr Lacaze) , Predictive Modelling Grant (Drs Fatkin, Kalman, Kistler, and Johnson) ; NSW Health: (Drs Fatkin and Johnson) . The ASPirin in Reducing Events in the Elderly (ASPREE) study was supported by a Flagship cluster grant (including the Commonwealth Scientific and Industrial Research Organisation, Monash University, Menzies Research Institute, Australian National University, and University of Melbourne) , by grants (U01AG029824 and U19AG062682) from the National Institute on Aging and the National Cancer Institute at the National Institutes of Health, by grants (334047 and 1127060) from the NHMRC, and by Mon-ash University and the Victorian Cancer Agency.& nbsp;