Journal article
The cost-effectiveness of coronary calcium score-guided statin therapy initiation for Australians with family histories of premature coronary artery disease
P Venkataraman, AL Neil, GK Mitchell, T Stanton, S Nicholls, AM Tonkin, GF Watts, TH Marwick
Medical Journal of Australia | Published : 2023
DOI: 10.5694/mja2.51860
Abstract
Objectives: To compare the cost-effectiveness of coronary artery calcium (CAC) score-guided statin therapy criteria and American College of Cardiology/American Heart Association (ACC/AHA) guidelines (10-year pooled cohort equation [PCE] risk ≥ 7.5%) with selection according to Australian guidelines (5-year absolute cardiovascular disease risk [ACVDR] ≥ 10%), for people with family histories of premature coronary artery disease. Study design, setting: Markov microsimulation state transition model based on data from the Coronary Artery calcium score: Use to Guide management of Hereditary Coronary Artery Disease (CAUGHT-CAD) trial and transition probabilities derived from published statin presc..
View full abstractGrants
Awarded by National Health and Medical Research Council
Funding Acknowledgements
This investigation was supported by a National Health and Medical Research Council project grant (GRT1080582) and a Postgraduate Scholarship for Prasanna Venkataraman (GRT1169357).