Long-term outcomes after endoscopic eradication therapy for dysplastic and T1a adenocarcinoma–related Barrett's esophagus: higher rate of late dysplastic recurrence with radiofrequency ablation monotherapy

Abstract

Background and Aims: There is conflicting literature describing the durability of complete remission of intestinal metaplasia (CRIM) after endoscopic eradication therapy for Barrett's esophagus (BE). The aim of this study was to assess the timeline, predictors, and long-term outcomes of recurrence. Methods: Data on 365 patients who underwent endoscopic eradication therapy for dysplastic BE were collected prospectively between 2008 and 2022 at a Barrett's referral unit. Kaplan-Meier method and Epanechnikov kernel density estimate were used to determine the cumulative incidence of recurrence after CRIM and the rate of recurrence over time. A logistic regression analysis was fitted to identify ..