Journal article
Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): Maternal Glycemia and Childhood Glucose Metabolism
Denise M Scholtens, Alan Kuang, Lynn P Lowe, Jill Hamilton, Jean M Lawrence, Yael Lebenthal, Wendy J Brickman, Peter Clayton, Ronald C Ma, David McCance, Wing Hung Tam, Patrick M Catalano, Barbara Linder, Alan R Dyer, William L Lowe, Boyd E Metzger, Chaicharn Deerochanawong, Thadchanan Tanaphonpoonsuk, Sukeeta Binratkaew, Uraiwan Chotigeat Show all
DIABETES CARE | AMER DIABETES ASSOC | Published : 2019
DOI: 10.2337/dc18-2021
Abstract
OBJECTIVE: This study examined associations of maternal glycemia during pregnancy with childhood glucose outcomes in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) cohort. RESEARCH DESIGN AND METHODS: HAPO was an observational international investigation that established associations of maternal glucose with adverse perinatal outcomes. The HAPO Follow-up Study included 4,832 children ages 10-14 years whose mothers had a 75-g oral glucose tolerance test (OGTT) at ∼28 weeks of gestation. Of these, 4,160 children were evaluated for glucose outcomes. Primary outcomes were child impaired glucose tolerance (IGT) and impaired fasting glucose (IFG). Additional outcomes were glucose-related m..
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Awarded by National Institute of Diabetes, Digestive, and Kidney Diseases
Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development
Awarded by National Institutes of Health's National Center for Advancing Translational Sciences
Funding Acknowledgements
The HAPO FUS is funded by grant 1U01-DK-094830 from the National Institute of Diabetes, Digestive, and Kidney Diseases and the Eunice Kennedy Shriver National Institute of Child Health and Human Development. The HAPO Study was funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (grants R01-HD-34242 and R01-HD-34243). HAPO FUS data were collected and managed using REDCap electronic data capture tools hosted at Northwestern University Feinberg School of Medicine. REDCap is supported at Feinberg School of Medicine by the Northwestern University Clinical and Translational Science Institute. Research reported in this publication was supported, in part, by the National Institutes of Health's National Center for Advancing Translational Sciences (grant UL1-TR-001422).