Journal article
Factors impacting time to ileostomy closure after anterior resection: the UK closure of ileostomy timing cohort study (CLOSE-IT)
K Gash, PG Vaughan-Shaw, J Brown, K Adams, AE Valiance, Jared Torkington, K Morris, JA Cornish, Adam Chambers, Adam Stearns, Adam Walsh, Adeline Rankin, Aftab Khan, Alastair Morton, Alec Engledow, Alex Newman, Alex Shaw, Alex Wilkins, Alexander Curtis, Alexander Jones Show all
COLORECTAL DISEASE | WILEY | Published : 2021
DOI: 10.1111/codi.15531
Abstract
AIM: Delay to closure of ileostomy following anterior resection for rectal cancer may impair postoperative bowel function and quality of life. We analysed time to ileostomy closure across the UK and investigated factors delaying closure. METHODS: For the retrospective cohort we assessed time to closure and incidence of non-closure for patients who underwent anterior resection with defunctioning ileostomy during 2015. Multivariate linear/Cox regression analyses were performed. For the prospective cohort we captured patients undergoing ileostomy closure during a 3-month period in 2018 to validate retrospective findings. RESULTS: The retrospective cohort involved 788 patients of whom 669 (84.9%..
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Awarded by MRC
Funding Acknowledgements
The project was funded by Tenovus Cancer Care, Wales. The funder had no influence on study design; in the collection, analysis and interpretation of data; in the writing of the report; and in the decision to submit the article for publication.