Journal article

Formal thought disorder in people at ultra-high risk of psychosis

A Demjaha, S Weinstein, D Stahl, F Day, L Valmaggia, G Rutigliano, A De Micheli, P Fusar-Poli, P McGuire

Bjpsych Open | Published : 2017

Abstract

Background Formal thought disorder is a cardinal feature of psychosis. However, the extent to which formal thought disorder is evident in ultra-high-risk individuals and whether it is linked to the progression to psychosis remains unclear. Aims Examine the severity of formal thought disorder in ultra-high-risk participants and its association with future psychosis. Method The Thought and Language Index (TLI) was used to assess 24 ultra-high-risk participants, 16 people with first-episode psychosis and 13 healthy controls. Ultra-high-risk individuals were followed up for a mean duration of 7 years (s.d.=1.5) to determine the relationship between formal thought disorder at baseline and transit..

View full abstract

University of Melbourne Researchers

Grants

Funding Acknowledgements

This work was supported by the UK Medical Research Council and the National Institute for Health Research (NIHR) Mental Health Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health. The Outreach and Support in South London (OASIS) service was supported by the Guy's and St Thomas' Charitable Foundation, South London and Maudsley Trust.