Journal article
Use of platelet transfusions and tranexamic acid in patients with myelodysplastic syndromes: A clinical practice survey
A Mo, R Weinkove, EM Wood, J Shortt, A Johnston, ZK McQuilten
European Journal of Haematology | WILEY | Published : 2024
DOI: 10.1111/ejh.14156
Abstract
Aim: Thrombocytopenia and bleeding are common in myelodysplastic syndromes (MDS), but optimal management is unknown. We conducted a survey to identify current clinical practice regarding platelet transfusion (PLT-T) and tranexamic acid (TXA) to inform future trial design. Method: A 25-question survey was distributed to members of the ALLG from December 2020 to July 2021. Results: Sixty-four clinicians across Australia, New Zealand and Singapore responded. Clinicians treated a median of 15 MDS patients annually. Twenty-nine (45%) reported having institutional guidelines regarding prophylactic PLT-T. Although 60 (94%) said they would consider using TXA, most (58/64; 91%) did not have instituti..
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Funding Acknowledgements
The authors acknowledge the ALLG Supportive Care Scientific Working Party for assisting in the development and piloting of the survey questions, and Tracey Gerber from ALLG for distribution of the survey to ALLG members. Open access publishing facilitated by Monash University, as part of the Wiley - Monash University agreement via the Council of Australian University Librarians.