Journal article

Defining the challenges and opportunities for using patient-derived models in prostate cancer research

W Nathaniel Brennen, Clementine Le Magnen, Sofia Karkampouna, Nicolas Anselmino, Nathalie Bock, Nicholas Choo, Ashlee K Clark, Ilsa M Coleman, Robin Dolgos, Alison M Ferguson, David L Goode, Marianna Krutihof-de Julio, Nora M Navone, Peter S Nelson, Edward O'Neill, Laura H Porter, Weranja Ranasinghe, Takuro Sunada, Elizabeth D Williams, Lisa M Butler Show all

Prostate | Wiley | Published : 2024

Abstract

Background: There are relatively few widely used models of prostate cancer compared to other common malignancies. This impedes translational prostate cancer research because the range of models does not reflect the diversity of disease seen in clinical practice. In response to this challenge, research laboratories around the world have been developing new patient-derived models of prostate cancer, including xenografts, organoids, and tumor explants. Methods: In May 2023, we held a workshop at the Monash University Prato Campus for researchers with expertise in establishing and using a variety of patient-derived models of prostate cancer. This review summarizes our collective ideas on how pat..

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Awarded by Department of Health and Human Services acting through the Victorian Cancer Agency


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Awarded by Swiss Cancer Research Foundation


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Awarded by Swiss National Science Foundation


Awarded by Medical Research Future Fund(MRFF) Rapid Applied Research Translation Program (Centre for Personalised Analysis of Cancers)


Awarded by The 3RCC


Awarded by PHRT


Awarded by PCUK Career Acceleration Fellowship


Awarded by NIH-SKCCC Cancer Center Support Grant


Awarded by Beat Cancer SA Beat Cancer Project Principal Cancer Research Fellowship


Awarded by Hospital Research Foundation


Awarded by Cancer Council NSW


Awarded by Priority-driven Collaborative Cancer Research Scheme


Awarded by Advance Queensland Industry Research Fellowship


Awarded by Tour De Cure Pioneering Grant


Awarded by LINC Grant


Awarded by Marie Sklodowska-Curie grant


Awarded by Victorian Cancer Agency Mid-Career Fellowship


Awarded by Swiss National Science Foundation (SNF)


Funding Acknowledgements

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