Journal article
Enhancing enantioselectivity in chiral metal organic framework fluorescent sensors
S Thoonen, P Siripanich, L Hua, HM Tay, P Ramkissoon, TA Smith, M Lessio, C Hua
Inorganic Chemistry Frontiers | Published : 2024
DOI: 10.1039/d4qi00760c
Abstract
The straightforward identification of enantiomers is of large importance to applications in the pharmaceutical, food and agricultural industries. We report the incorporation of two ligands containing the 1,1′-binaphthyl (BINOL) core with axial chirality and d-camphoric acid containing point chirality into Zn(ii) metal-organic framework (MOF) chiral fluorescence sensors. The Zn(ii) MOFs displayed outstanding enantioselectivity as chiral fluorescent sensors with an exceptional enantiomeric ratio (ER) of 3.92 which is amongst the highest values reported, along with excellent accuracy for the determination of enantiomeric excess in unknown samples. The role of complementary void shapes, a chiral..
View full abstractGrants
Awarded by University of New South Wales
Funding Acknowledgements
This research was conducted by the Australian Research Council Centre of Excellence in Exciton Science (project number CE170100026) and funded by the Australian Government. We are grateful for the computational resources and services from the National Computational Infrastructure (NCI), provided by the Australian government and the computational cluster Katana supported by the Research Technology Services at UNSW Sydney.