Journal article
Characterising HIV-1 transmission in Victoria, Australia: a molecular epidemiological study
G Taiaroa, D Chibo, S Herman, ML Taouk, M Gooey, J D'Costa, R Sameer, N Richards, E Lee, L Macksabo, N Higgins, DJ Price, S Jen Low, E Steinig, GE Martin, MA Moso, L Caly, J Prestedge, CK Fairley, EPF Chow Show all
Lancet Regional Health Western Pacific | ELSEVIER | Published : 2024
Abstract
Background: In Australia the incidence of HIV has declined steadily, yet sustained reduction of HIV transmission in this setting requires improved public health responses. As enhanced public health responses and prioritisation of resources may be guided by molecular epidemiological data, here we aimed to assess the applicability of these approaches in Victoria, Australia. Methods: A comprehensive collection of HIV-1 pol sequences from individuals diagnosed with HIV in Victoria, Australia, between January 1st 2000 and December 31st 2020 were deidentified and used as the basis of our assessment. These sequences were subtyped and surveillance drug resistance mutations (SDRMs) identified, before..
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Awarded by Australian Research Council
Funding Acknowledgements
We would like to acknowledge all members of the relevant NHMRC Partnership Grant, with this work bene fi ting greatly from the dis-cussions and feedback provided by the investigator group throughout the planning, analysis and communication of this research. particular, we would like to thank the representatives from community organisations for their engagement and support: Aaron Cogle (Na-tional Association of People with HIV Australia) , Richard Keane (Living Positive Victoria) , Simon Ruth and Colin Batrouney (Thorne Harbour Health) . We would also like to acknowledge the engagement and input of Dr Kirsty Machon (Positive Women Victoria) . We thank Dr. Mark Schultz for his work on initial Victorian HIV-1 sequence analyses. SRL was supported by an Australian National Health and Medical Research Council (NHMRC) Practitioner Fellowship, NHMRC Program Grant and NHMRC Investigator Fellowship during the course of the project. EPFC, CKF, and DAW were supported NHMRC Investigator Grants (GNT1172873, GNT1172900 and GNT1174555, respectively) and SD by the Australian Research Council (FT220100629) and NHMRC (2017284) .