Journal article

Characterization and individual-level prediction of cognitive state in the first year after ‘mild’ stroke

JP Saa, T Tse, GCH Koh, P Yap, CM Baum, DE Uribe-Rivera, SM Windecker, H Ma, SM Davis, GA Donnan, LM Carey

Plos One | PUBLIC LIBRARY SCIENCE | Published : 2024

Abstract

Background Mild stroke affects more than half the stroke population, yet there is limited evidence characterizing cognition over time in this population, especially with predictive approaches applicable at the individual-level. We aimed to identify patterns of recovery and the best combination of demographic, clinical, and lifestyle factors predicting individual-level cognitive state at 3- and 12-months after mild stroke. Methods In this prospective cohort study, the Montreal Cognitive Assessment (MoCA) was administered at 3–7 days, 3- and 12-months post-stroke. Raw changes in MoCA and impairment rates (defined as MoCA<24 points) were compared between assessment time-points. Trajectory clust..

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Grants

Awarded by Commonwealth Scientific and Industrial Research Organisation


Funding Acknowledgements

START was supported by a Flagship Collaboration Fund through the Preventative Health Flagship and Commonwealth Scientific and Industrial Research Organisation (CSIRO) of Australia. Write-up was supported by the James S .McDonnell Foundation (grant# 220020413); the National Health and Medical Research Council (NHMRC) of Australia (GNT1077898; GNT1153236; GNT2004443); and La Trobe University (La Trobe Full-Fee Research, LTUFFR, and La Trobe Postgraduate Research, LTUPR scholarships)