Eccentricity Dependency of Retinal Electrophysiological Deficits in People With Episodic Migraine

Abstract

PURPOSE. During the non-attack period, people with migraine may show retinal dysfunction. This study builds on previous work by exploring the possibility of foveal and non-foveal visual field and electroretinographic deficits and determining the overlap in eccentricity of such localized visual deficits in people with migraine. METHODS. Visual fields and multifocal electroretinography (mf-ERG) were tested in 27 people with migraine (aged 19–45 years) and 18 non-headache controls (aged 20–46 years). Data were averaged according to 5 concentric rings at 0.05). In contrast, the non-foveal mf-ERG was reduced in amplitude in people with migraine relative to controls (P < 0.001), and this group di..