Journal article
Comorbidity of postural orthostatic tachycardia syndrome and chronic fatigue syndrome in an Australian cohort
GK Reynolds, DP Lewis, AM Richardson, BA Lidbury
JOURNAL OF INTERNAL MEDICINE | WILEY | Published : 2014
DOI: 10.1111/joim.12161
Abstract
OBJECTIVE: Patients with chronic fatigue syndrome (CFS) are frequently diagnosed with comorbid postural orthostatic tachycardia syndrome (POTS), suggesting a shared pathogenesis. The aim of this study was to examine the relationship between demographic characteristics, autonomic functioning and fatigue levels amongst CFS patients with and without comorbid POTS. DESIGN AND SETTING: All patients presenting to the CFS Discovery Clinic between 2009 and 2012 completed a 20-min standing task as part of their initial assessment. Heart rate and pulse pressure were recorded at baseline, at 2-min intervals poststanding, at the end of the task and following a recovery period. Average heart rate and pul..
View full abstractGrants
Funding Acknowledgements
This study was supported by the Alison Hunter Memorial Foundation and the Medical Advances Without Animals Trust. The sponsors had no direct involvement in designing the study, data collection and analysis or drafting the final version of the manuscript. We wish to thank the nursing and administrative staff at CFS Discovery (Donvale, Victoria) for their assistance throughout the project. We are also grateful to Drs Marco Ruggiero and Stefania Pacini (The University of Florence, Italy) for helpful suggestions regarding interpretation of the haemodynamic data.