Journal article
Utility of icobrain for brain volumetry in multiple sclerosis clinical practice
AL Nguyen, MP Sormani, D Horakova, EH Havrdova, MH Barnett, N De Stefano, M Battaglini, M Vaneckova, E Lui, F Gaillard, PM Desmond, H Prime, M Datta, A Van der Walt, VG Jokubaitis, F Podevyn, R Zivadinov, B Weinstock-Guttman, MB D'hooghe, G Nagels Show all
Multiple Sclerosis and Related Disorders | Elsevier BV | Published : 2024
Open access
Abstract
Background: Few studies on multiple sclerosis (MS) have explored the variability of percentage brain volume change (PBVC) measurements obtained from different clinical MRIs. In a retrospective multicentre cohort study, we quantified the variability of annualised PBVC in clinical MRIs. Methods: Clinical MRIs of relapse-onset MS patients were assessed by icobrain. Volumetric data were analysed on same-scanner and different-scanner MRI pairs if they passed quality control criteria. Alignment similarity between two images had to be comparable to same-scanner scan-rescan images. Results: Of 6826 MRIs, 85 % had appropriate volumetric sequences and 4446 serial MRI pairs were analysed. 3334 (75 %) M..
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