Pentoxifylline for the treatment of endometriosis-associated pain and infertility

Abstract

Background: Endometriosis is a chronic inflammatory condition that occurs during the reproductive years. It is characterised by endometrium-like tissue developing outside the uterine cavity. This endometriotic tissue development is dependent on oestrogen produced primarily by the ovaries and partially by the endometriotic tissue itself, therefore traditional management has focused on ovarian suppression. In this review we considered the role of modulation of the immune system as an alternative approach. This is an update of a Cochrane Review previously published in 2012. Objectives: To determine the effectiveness and safety of pentoxifylline in the management of endometriosis. Search methods..