Puberty and NeuroDevelopment in adolescents (PANDA): a study protocol

KO Bray; O Durbin; S Hartanto; M Khetan; D Liontos; SJ Manuele; I Zwaan; D Ganella; MM Herting; JH Kim; M O’Connell; E Pozzi; O Schwartz; M Seal; J Simmons; N Vijayakumar; S Whittle

Journal article

Puberty and NeuroDevelopment in adolescents (PANDA): a study protocol

KO Bray, O Durbin, S Hartanto, M Khetan, D Liontos, SJ Manuele, I Zwaan, D Ganella, MM Herting, JH Kim, M O’Connell, E Pozzi, O Schwartz, M Seal, J Simmons, N Vijayakumar, S Whittle

BMC Pediatrics | Published : 2024

DOI: 10.1186/s12887-024-05197-w

Abstract

Background: Biopsychosocial changes during adolescence are thought to confer risk for emotion dysregulation, and in particular, anxiety disorders. However, there are substantial gaps in our knowledge about the biological mechanisms underlying anxiety during adolescence, and whether this contributes to the higher prevalence in females. The Puberty and NeuroDevelopment in Adolescents (PANDA) study aims to examine links between biological (sex hormones, cortisol) and social environmental factors and brain function during adolescence, with a focus on key processes (emotion regulation, fear learning) identified as relevant for the development of anxiety disorders. Methods: PANDA is a cross-sectio..

View full abstract

University of Melbourne Researchers

Elena Pozzi Author

Orli Schwartz Author

Marc L Seal Author

Julian Simmons Author

Related Projects (1)

NEURAL MECHANISMS OF ANXIETY ACROSS DEVELOPMENT AND SEX

Anxiety disorders are extremely debilitating, and are most likely to have their onset in young people. Understanding the biological mechanis..

Grants

Awarded by Murdoch Children's Research Institute

Funding Acknowledgements

We would like to thank all the young people and their families who participated in the study. We would like to thank the Murdoch Children's Research Institute Developmental Imaging group and Magnetic Resonance staff at the Royal Children's Hospital.