The long-term sustainability of a pharmacist-led antimicrobial stewardship penicillin allergy delabelling ward round: A prospective cohort study

Abstract

Objectives Inpatient penicillin allergy is associated with inappropriate antibiotic prescribing and adverse patient outcomes. We reviewed the long-term effectiveness, safety and antimicrobial stewardship impacts of a pharmacist-led penicillin allergy delabelling ward round. Methods Adult inpatients with a penicillin allergy label were evaluated during a pharmacist-led penicillin allergy ward round implemented within a tertiary referral health service in Melbourne, Australia for more than three years. Using the validated Antibiotic Allergy Assessment Tool (AAAT) and PEN-FAST clinical decision rule, patients with a low-risk penicillin allergy or PEN-FAST score <3, were offered a single-dose di..