Journal article
The genomic and epigenomic landscapes of hemizygous genes across crops with contrasting reproductive systems
Y Peng, Y Wang, Y Liu, X Fang, L Cheng, Q Long, D Su, T Zhang, X Shi, X Xu, Q Xu, N Wang, F Zhang, Z Liu, H Xiao, J Yao, L Tian, W Hu, S Chen, H Wang Show all
Proceedings of the National Academy of Sciences of the United States of America | Published : 2025
Abstract
Hemizygous genes, which are present on only one of the two homologous chromosomes of diploid organisms, have been mainly studied in the context of sex chromosomes and sex-linked genes. However, these genes can also occur on the autosomes of diploid plants due to structural variants (SVs), such as a deletion/insertion of one allele, and this phenomenon largely unexplored in plants. Here, we investigated the genomic and epigenomic landscapes of hemizygous genes across 22 genomes with varying propagation histories: eleven clonal lineages, seven outcrossed samples, and four inbred and putatively homozygous genomes. We identified SVs leading to genic hemizygosity. As expected, very few genes (0.0..
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Awarded by National Natural Science Foundation of China