Endovascular neural stimulation with platinum and platinum black modified electrodes

Abstract

Recent work has shown the ability to record neural behaviour in pre-clinical studies from an endovascular location for over a year. Previous work on stimulating neural tissue from an endovascular location has also shown motor-evoked responses in sheep. However, endovascular stimulation requires high currents and can result in electrode degradation. This study aimed to modify an endovascular electrode to increase its charge injection capacity for efficacious neural stimulation. The platinum endovascular electrode was modified with platinum black and characterised by electrochemical and microscopic techniques. The stability of the electrode coating was assessed after a 7-day continuous stimula..