Journal article
Does oxygen pulse represent a reliable surrogate for stroke volume during exercise? Insights from cardiopulmonary exercise test combined with echocardiography or invasive measurements
M Milani, Y Bekhuis, M Falter, S Moura-Ferreira, S Hoedemakers, W L Hoyes, S Foulkes, M Haykowsky, J Stassen, R Jasaityte, A La Gerche, D Hansen, G Claessen, L Herbots, J Verwerft
European Journal of Preventive Cardiology | Oxford University Press (OUP) | Published : 2025
Abstract
Abstract Background While interpreting the mechanisms underlying exercise limitation in cardiopulmonary exercise testing (CPET), oxygen pulse (O2pulse) is often assumed to be a surrogate for stroke volume (SV). However, in the rearranged Fick’s equation, O2pulse represents the product of SV and arteriovenous oxygen difference (a-vO2diff). Consequently, interpreting O2pulse exclusively as a reflection of SV can be misleading, as it disregards one of its key determinants. Purpose To assess the effort response of the determinants of O2pulse (SV and a-vO2Diff) by simultaneous C..
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