Pharmacological and dietary treatments for developmental stuttering: A systematic review

Abstract

Introduction: Pharmacological and dietary treatments are increasingly investigated as alternatives or adjuncts to behavioural therapy for developmental stuttering. However, their relative efficacy, acceptability, tolerability and safety remain unclear. This systematic review evaluated the evidence for these treatments. Methods: We searched CENTRAL, MEDLINE, Embase, Cochrane and other databases from inception to June 2024 for studies examining pharmacological or dietary treatments for developmental stuttering. We did not limit studies by design. Primary outcomes included clinician-rated and self-reported measures of stuttering severity and frequency. Risk of bias was assessed using the Cochra..