Journal article

Efficacy and Moderators of Cognitive Behavioural Therapy for Psychosis Versus Other Psychological Interventions: An Individual-Participant Data Meta-Analysis.

David T Turner, Mirjam Reijnders, Mark van der Gaag, Eirini Karyotaki, Lucia R Valmaggia, Steffen Moritz, Tania Lecomte, Douglas Turkington, Rafael Penadés, Helio Elkis, Corinne Cather, Frances Shawyer, Kieron O'Connor, Zhan-Jiang Li, Eliza Martha de Paiva Barretto, Pim Cuijpers

Focus (Am Psychiatr Publ) | American Psychiatric Association Publishing | Published : 2025

Abstract

BACKGROUND: Study-level meta-analyses have demonstrated the efficacy of cognitive-behavioural therapy for psychosis (CBTp). Limitations of conventional meta-analysis may be addressed using individual-participant-data (IPD). We aimed to determine a) whether results from IPD were consistent with study-level meta-analyses and b) whether demographic and clinical characteristics moderate treatment outcome. METHODS: We systematically searched PubMed, Embase, PsychInfo and CENTRAL. Authors of RCTs comparing CBTp with other psychological interventions were contacted to obtain original databases. Hierarchical mixed effects models were used to examine efficacy for psychotic symptoms. Patient character..

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University of Melbourne Researchers