Prenatal Intravenous Iron and Child Growth A Secondary Analysis of a Randomized Clinical Trial

Abstract

IMPORTANCE Maternal anemia during pregnancy is associated with poor growth during early childhood, but it remains unclear whether treatment using intravenous iron could enhance child growth. OBJECTIVE To evaluate whether intravenous ferric carboxymaltose (FCM) treatment for moderate to severe anemia during the second trimester of pregnancy enhances postnatal child growth compared with standard-of-care (SOC) oral iron. DESIGN, SETTING, AND PARTICIPANTS This was a prespecified secondary analysis of a randomized clinical trial (Randomized Controlled Trial of the Effect of Intravenous Iron on Anaemia in Malawian Pregnant Women [REVAMP]). In REVAMP, pregnant women with capillary hemoglobin betwee..