Mortality trends for sepsis and septic shock among critically ill adults in Australia and New Zealand

AP Poole; A Chaba; R Bellomo; M Bailey; A Deane; A Delaney; G Eastwood; K Haines; N Hammond; T Hensman; A Higgins; D Jones; Z McQuilten; C Mendis; A Serpa Neto; D Pilcher; M Saxena; K Shekar; K Thompson; PJ Young; E Litton; AA Udy

Journal article

Mortality trends for sepsis and septic shock among critically ill adults in Australia and New Zealand

AP Poole, A Chaba, R Bellomo, M Bailey, A Deane, A Delaney, G Eastwood, K Haines, N Hammond, T Hensman, A Higgins, D Jones, Z McQuilten, C Mendis, A Serpa Neto, D Pilcher, M Saxena, K Shekar, K Thompson, PJ Young Show all

Intensive Care Medicine | Published : 2025

DOI: 10.1007/s00134-025-08162-y

Abstract

Purpose: Sepsis is a major cause of mortality in intensive care unit (ICU) patients. Significant temporal improvements in survival were observed in Australia and New Zealand (ANZ) from 2000 to 2012. Whether this has continued remains uncertain, and current sepsis-related mortality in ANZ ICUs is unknown. Methods: We studied adult ICU patients admitted with sepsis (based on the 3rd international consensus definition for sepsis and septic shock), between January 2000 and June 2023. Data were obtained from 219 ICUs that contributed to the ANZ Intensive Care Society Adult Patient Database. We used logistic regression models to study changes in in-hospital mortality over time. Results: Among 2,97..

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