Ultra-flexible Coil for Wireless Endovascular Cortical Stimulation

Abstract

Endovascular devices hold promise for minimally invasive neural stimulation, particularly for applications in the treatment of neurological disorders. We developed a fully wireless endovascular neural stimulator with a novel coil design implemented on a mesh structure to achieve ultra-flexibility. The device was successfully implanted into the superior sagittal sinus of a sheep model via a minimally invasive catheter procedure, demonstrating its adaptability to curved and narrow cerebral veins. Wireless power transfer efficiency (PTE) was analyzed theoretically, simulated, and validated through benchtop and animal experiments. Neural stimulation achieved using pulse-modulation from external ..