Peri-operative risk of non-cardiac surgery in patients with aortic stenosis: a systematic review and meta-analysis

Abstract

Introduction: Aortic stenosis is a risk factor for adverse outcomes following non-cardiac surgery; however, existing data regarding peri-operative morbidity and mortality in this patient cohort remain conflicted. This systematic review and meta-analysis aimed to quantify the peri-operative risks in patients with aortic stenosis undergoing non-cardiac surgery. Methods: Following the development of our search strategy, we searched databases for relevant studies. The primary endpoint was all-cause in-hospital or 30-day mortality associated with aortic stenosis in patients undergoing non-cardiac surgery. Secondary endpoints included: myocardial infarction; heart failure; stroke; delirium; venous..